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Effects of lovastatin (mevinolin) on sterol levels and on activity of azoles in Saccharomyces cerevisiae.

The hypocholesterolemic drug lovastatin (mevinolin) was found to be very effective in lowering the sterol levels of the wild-type yeast Saccharomyces cerevisiae. Lovastatin dramatically decreased the steryl ester content from 2.62 to 0.8 micrograms/mg (dry weight), whereas the free sterol content de...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Lorenz, R T, Parks, L W
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171901/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2285278/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.9.1660
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