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Mode of action of tubulozoles against Plasmodium falciparum in vitro.

The mode of action of the tubulozole isomers, recently recognized as a new class of potential antimalarial agents, was investigated. Whereas neither glycolysis, protease activity, or nucleic acid biosynthesis was primarily affected, protein biosynthesis decreased soon after addition of the drug. Inh...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Dieckmann-Schuppert, A, Franklin, R M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171867/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2221861/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.8.1529
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