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Plasmid-encoded MucB protein is a DNA polymerase (pol RI) specialized for lesion bypass in the presence of MucA′, RecA, and SSB

Replication through damaged sites in DNA requires in Escherichia coli the SOS stress-inducible DNA polymerase V (UmuC), which is specialized for lesion bypass. Homologs of the umuC gene were found on native conjugative plasmids, which often carry multiple antibiotic-resistant genes. MucB is a UmuC h...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Goldsmith, Moshe, Sarov-Blat, Lea, Livneh, Zvi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC17182/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11016960/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.200361997
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