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Pharmacokinetics of 3'-fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine in rhesus monkeys.

3'-Fluoro-3'-deoxythymidine and 3'-deoxy-2',3'-didehydrothymidine are nucleoside analogs which inhibit human and simian immunodeficiency virus in vitro. The pharmacokinetic properties of these compounds in rhesus monkeys after intravenous, oral, and subcutaneous administration of the drug were compa...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Schinazi, R F, Boudinot, F D, Doshi, K J, McClure, H M
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168144/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1214
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