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Intracellular accumulation of azithromycin by cultured human fibroblasts.

Azithromycin was shown to achieve high concentrations in human skin fibroblasts. Intracellular penetration occurred rapidly (10 micrograms/mg of cellular protein after 3 h) and then increased progressively over a 3-day period; azithromycin accumulated up to 21 times more than erythromycin (61.1 vers...

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Détails bibliographiques
Publié dans:Antimicrob Agents Chemother
Auteurs principaux: Gladue, R P, Snider, M E
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1990
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171758/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.1056
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