Pathogenicity for humans of human rhinovirus type 2 mutants resistant to or dependent on chalcone Ro 09-0410.

Mutants of human rhinovirus type 2 (HRV-2) resistant to and dependent on the antirhinoviral compound chalcone Ro 09-0410 were selected in cell culture under clean laboratory conditions. A total of 42 volunteers were challenged with either the drug-resistant mutant [SR2-410(r)] (15 volunteers), the d...

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Publié dans:	Antimicrob Agents Chemother
Auteurs principaux:	Yasin, S R, al-Nakib, W, Tyrrell, D A
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1990
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171738/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168152/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.6.963
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