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Berberine derivatives as antileishmanial drugs.

Berberine, a quaternary alkaloid, and several of its derivatives were tested for efficacy against Leishmania donovani and Leishmania braziliensis panamensis in golden hamsters. Tetrahydroberberine was less toxic and more potent than berberine against L. donovani but was not as potent as meglumine an...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Vennerstrom, J L, Lovelace, J K, Waits, V B, Hanson, W L, Klayman, D L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171721/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2360830/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.5.918
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