Phosphorylation of the VP16 transcriptional activator protein during herpes simplex virus infection and mutational analysis of putative phosphorylation sites

VP16 is a virion phosphoprotein of herpes simplex virus and a transcriptional activator of the viral immediate-early (IE) genes. We identified four novel VP16 phosphorylation sites (Ser18, Ser353, Ser411, and Ser452) at late times in infection, but found no evidence of phosphorylation of Ser375, a r...

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Main Authors: Ottosen, Søren, Herrera, Francisco J., Doroghazi, James R., Hull, Angela, Mittal, Sheenu, Lane, William S., Triezenberg, Steven J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2005
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1717022/
https://ncbi.nlm.nih.gov/pubmed/16297954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2005.10.011
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