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Nucleic acid-triggered catalytic drug release

We propose a concept for the rational design and synthesis of highly selective chemotherapeutic agents that makes direct use of genetic information about the disease state. The key idea is to use the mRNA or DNA specific to the disease state to trigger the catalytic release of a cytotoxic drug by pr...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Ma, Zhaochun, Taylor, John-Stephen
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: The National Academy of Sciences 2000
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC17170/
https://ncbi.nlm.nih.gov/pubmed/11027325
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