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Evaluation of nikkomycins X and Z in murine models of coccidioidomycosis, histoplasmosis, and blastomycosis.

Nikkomycins X and Z, competitive inhibitors of fungal chitin synthase, were evaluated as therapeutic agents in vitro and in mouse models of coccidioidomycosis, histoplasmosis, and blastomycosis. In vitro, the nikkomycins were found to be most effective against the highly chitinous, dimorphic fungi C...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Hector, R F, Zimmer, B L, Pappagianis, D
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171648/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2344165/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.4.587
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