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In vitro and in vivo activities of a new quinolone, WIN 57273, possessing potent activity against gram-positive bacteria.

The antibacterial activity of a new 7-dimethylpyridinyl quinolone, WIN 57273, was assessed by using in vitro and in vivo models. Agar inclusion and broth dilution in vitro tests revealed broad-spectrum activity against gram-positive and selected gram-negative organisms, with the greatest potency obs...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Principais autores: Sedlock, D M, Dobson, R A, Deuel, D M, Lesher, G Y, Rake, J B
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1990
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171645/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2344163/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.4.568
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