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Effects of dosage, peak and trough concentrations in serum, protein binding, and bactericidal rate on efficacy of teicoplanin in a rabbit model of endocarditis.

The effect of dosage and the relative importance of peak and trough concentrations in serum for efficacy of teicoplanin were examined in a rabbit model of aortic valve endocarditis. Concentrations of teicoplanin in serum exceeded the MIC by several hundredfold, yet teicoplanin was less rapidly bacte...

詳細記述

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Chambers, H F, Kennedy, S
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1990
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171634/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2140496/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.4.510
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