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Influence of N substitution on antimycobacterial activity of ciprofloxacin.

Ciprofloxacin analogs with various substitutions on the piperazine nitrogen were tested against several mycobacteria. In contrast to what has been found with other gram-positive and gram-negative bacteria, alkyl analogs such as N-isopropylciprofloxacin were shown to be significantly more active than...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Haemers, A, Leysen, D C, Bollaert, W, Zhang, M Q, Pattyn, S R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171627/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2334166/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.3.496
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