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Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing

Unraveling the mechanisms controlling remnant lipoprotein clearance is important, as these lipoproteins are highly atherogenic. The most critical molecule in this process is apoE, which mediates high-affinity binding of remnant lipoproteins to members of the LDL receptor (LDLR) family and cell-surfa...

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Detalles Bibliográficos
Main Authors: Mahley, Robert W., Huang, Yadong
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716223/
https://ncbi.nlm.nih.gov/pubmed/17200713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30889
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