Myd88-dependent positioning of Ptgs2-expressing stromal cells maintains colonic epithelial proliferation during injury

We identified cellular and molecular mechanisms within the stem cell niche that control the activity of colonic epithelial progenitors (ColEPs) during injury. Here, we show that while WT mice maintained ColEP proliferation in the rectum following injury with dextran sodium sulfate, similarly treated...

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Main Authors: Brown, Sarah L., Riehl, Terrence E., Walker, Monica R., Geske, Michael J., Doherty, Jason M., Stenson, William F., Stappenbeck, Thaddeus S.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Clinical Investigation 2007
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716207/
https://ncbi.nlm.nih.gov/pubmed/17200722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI29159
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