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A Caspase-Resistant Form of Bcl-X(L), but Not Wild Type Bcl-X(L), Promotes Clonogenic Survival After Ionizing Radiation
Bcl-2 and Bcl-X(L) belong to a family of proteins overexpressed in a variety of human cancers which inhibit apoptosis in response to a number of stimuli including chemotherapeutic agents and ionizing radiation. To better understand the role of these polypeptides in modulating the response of cancer...
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Autori principali: | , , , , , , |
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Natura: | Artigo |
Lingua: | Inglês |
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Stockton Press
1999
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1716057/ https://ncbi.nlm.nih.gov/pubmed/10935471 |
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