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A Caspase-Resistant Form of Bcl-X(L), but Not Wild Type Bcl-X(L), Promotes Clonogenic Survival After Ionizing Radiation

Bcl-2 and Bcl-X(L) belong to a family of proteins overexpressed in a variety of human cancers which inhibit apoptosis in response to a number of stimuli including chemotherapeutic agents and ionizing radiation. To better understand the role of these polypeptides in modulating the response of cancer...

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Autors principals: Rehemtulla, Alnawaz, Hamilton, A Christin, Taneja, Neelam, Fridman, Jordan, Juan, Todd SC, Maybaum, Jonathan, Chinnaiyan, Arul
Format: Artigo
Idioma:Inglês
Publicat: Stockton Press 1999
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1716057/
https://ncbi.nlm.nih.gov/pubmed/10935471
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