Caricamento...
Role of the NEDD8 Modification of Cul2 in the Sequential Activation of ECV Complex
ECV is an E3 ubiquitin ligase complex, which is composed of elongins B and C, Rbx1, Cul2, and the substrate-conferring von Hippel-Lindau (VHL) tumorsuppressor protein that targets the catalytic α subunit of hypoxia-inducible factor (HIF) for oxygen-dependent ubiquitin-mediated destruction. Mutations...
Salvato in:
Autori principali: | , |
---|---|
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Neoplasia Press Inc.
2006
|
Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1716018/ https://ncbi.nlm.nih.gov/pubmed/17132228 |
Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|