Loading...
Role of the NEDD8 Modification of Cul2 in the Sequential Activation of ECV Complex
ECV is an E3 ubiquitin ligase complex, which is composed of elongins B and C, Rbx1, Cul2, and the substrate-conferring von Hippel-Lindau (VHL) tumorsuppressor protein that targets the catalytic α subunit of hypoxia-inducible factor (HIF) for oxygen-dependent ubiquitin-mediated destruction. Mutations...
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Neoplasia Press Inc.
2006
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1716018/ https://ncbi.nlm.nih.gov/pubmed/17132228 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|