Synergistic effect of ganciclovir and foscarnet on cytomegalovirus replication in vitro.

Ganciclovir and foscarnet possess substantial activity against cytomegalovirus. Both exhibit dose-limiting toxicity, which reduces their clinical usefulness. We demonstrated synergistic inhibition of cytomegalovirus replication in vitro by ganciclovir and foscarnet. Reduced-dose combination therapy...

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Detalhes bibliográficos

Publicado no:	Antimicrob Agents Chemother
Principais autores:	Manischewitz, J F, Quinnan, G V, Lane, H C, Wittek, A E
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1990
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171593/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2158278/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.2.373
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