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Staphylococcus aureus ventriculitis treated with single-dose intraventricular vancomycin or daptomycin (LY146032): bacterial and antibiotic kinetics in hydrocephalic rabbits.

Vancomycin and a new antibiotic, daptomycin (LY146032), were tested in vitro and in vivo against Staphylococcus aureus. In vivo tests were performed with rabbits with kaolin-induced hydrocephalus. Five groups of rabbits were studied: untreated ventriculitis, intraventricular vancomycin only, and ven...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Haworth, C S, Sobieski, M W, Scheld, W M, Park, T S
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 1990
Materias:
Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171566/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2158276/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.34.2.245
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