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Molecular genetics of phenylketonuria in Mediterranean countries: a mutation associated with partial phenylalanine hydroxylase deficiency.

We report the characterization of a mutation in the phenylalanine hydroxylase (PAH) gene associated with partial residual activity of the enzyme. This point mutation (280glu----lys) was found by sequencing a mutant cDNA clone derived from a needle biopsy of the liver in a child with variant form of...

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Hlavní autoři: Lyonnet, S, Caillaud, C, Rey, F, Berthelon, M, Frézal, J, Rey, J, Munnich, A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1989
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715570/
https://ncbi.nlm.nih.gov/pubmed/2564729
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