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Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5

Familial adenomatous polyposis (FAP), a Mendelian disorder that includes familial polyposis coli (FPC) and Gardner syndrome (GS), has an autosomal dominant mode of inheritance. It is characterized by hundreds to thousands of adenomatous polyps that can progress to carcinoma of the colon, suggesting...

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Bibliographic Details
Main Authors: Nakamura, Yusuke, Lathrop, Mark, Leppert, Mark, Dobbs, Marc, Wasmuth, John, Wolff, Erica, Carlson, Mary, Fujimoto, Esther, Krapcho, Karen, Sears, Tena, Woodward, Scott, Hughes, J., Burt, Randy, Gardner, Eldon, Lalouel, Jean-Marc, White, Ray
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715544/
https://ncbi.nlm.nih.gov/pubmed/2903664
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