Selection against lethal alleles in females heterozygous for incontinentia pigmenti.

Studies of five heterozygous females from three kindreds segregating incontinentia pigmenti indicate that cells expressing the mutation have been eliminated from skin fibroblast cultures and in varying degrees from hematopoietic tissues. Clonal analysis was carried out using G6PD variants and methyl...

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Detaylı Bibliyografya
Asıl Yazarlar: Migeon, B R, Axelman, J, Jan de Beur, S, Valle, D, Mitchell, G A, Rosenbaum, K N
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715454/
https://ncbi.nlm.nih.gov/pubmed/2562819
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