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Phenylalanine hydroxylase gene haplotypes in Polynesians: evolutionary origins and absence of alleles associated with severe phenylketonuria.

A total of 630 haplotypes for the phenylalanine hydroxylase (PAH) gene locus were established in five groups of Polynesians comprising Samoans, Tongans, Cook Islanders, Maori, and Niueans. Considerable genetic continuity was demonstrated between these widely dispersed populations, since three common...

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Autores principales: Hertzberg, M, Jahromi, K, Ferguson, V, Dahl, H H, Mercer, J, Mickleson, K N, Trent, R J
Formato: Artigo
Lenguaje:Inglês
Publicado: 1989
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715431/
https://ncbi.nlm.nih.gov/pubmed/2563633
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