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Analysis of DNA polymorphism haplotypes linked to the cystic fibrosis locus in North American black and Caucasian families supports the existence of multiple mutations of the cystic fibrosis gene.

Strong linkage disequilibrium (LD) was found between DNA marker XV2c and the cystic fibrosis (CF) locus (delta = 0.46) and between DNA marker KM19 and CF (delta = 0.67) in 157 CF and 138 normal chromosomes from U.S. Caucasians. DNA haplotypes with nine polymorphic sites were created in 54 Caucasian...

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Detaylı Bibliyografya
Asıl Yazarlar: Cutting, G R, Antonarakis, S E, Buetow, K H, Kasch, L M, Rosenstein, B J, Kazazian, H H
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715429/
https://ncbi.nlm.nih.gov/pubmed/2563631
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