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Primary cultures of renal epithelial cells from X-linked hypophosphatemic (Hyp) mice express defects in phosphate transport and vitamin D metabolism.

Mutation in a gene (symbol Hyp) on the X chromosome causes hypophosphatemia in the mouse. The murine phenotype is a counterpart of X-linked hypophosphatemia in man. Both exhibit impaired renal reabsorption of phosphate in vivo. In vitro studies in the Hyp mouse have shown decreased Na+-dependent pho...

詳細記述

保存先:
書誌詳細
主要な著者: Bell, C L, Tenenhouse, H S, Scriver, C R
フォーマット: Artigo
言語:Inglês
出版事項: 1988
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715381/
https://ncbi.nlm.nih.gov/pubmed/3414685
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