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Comparison of sequential and fixed-structure sampling of pedigrees in complex segregation analysis of a quantitative trait.
In designing a study to demonstrate the existence of a major locus for a quantitative trait, an investigator chooses a sampling rule to ascertain pedigrees. The choice of sampling rule can significantly affect the study's power. Here, we compare two types of sampling rules for family studies: f...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
1988
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1715370/ https://ncbi.nlm.nih.gov/pubmed/3414688 |
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