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Trisomy 21 (Down syndrome): studying nondisjunction and meiotic recombination by using cytogenetic and molecular polymorphisms that span chromosome 21.

By combining molecular and cytogenetic techniques, we demonstrated the feasibility and desirability of a comprehensive approach to analysis of nondisjunction for chromosome 21. We analyzed the parental origin and stage of meiotic errors resulting in trisomy 21 in each of five families by successfull...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Stewart, G D, Hassold, T J, Berg, A, Watkins, P, Tanzi, R, Kurnit, D M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1988
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715248/
https://ncbi.nlm.nih.gov/pubmed/2893544
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