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Efficient computations in multilocus linkage analysis.

This paper describes efficient methods for likelihood calculations and maximum-likelihood estimation in multilocus linkage analysis of reference families and general disease pedigrees, and it documents their performance as implemented in the LINKAGE programs. This information should be of considerab...

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Main Authors: Lathrop, G M, Lalouel, J M
格式: Artigo
語言:Inglês
出版: 1988
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1715153/
https://ncbi.nlm.nih.gov/pubmed/3162348
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