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Tissue concentrations and bioactivity of amphotericin B in cancer patients treated with amphotericin B-deoxycholate.

We have studied amphotericin B concentrations in tissues of 13 cancer patients who died after having received 75 to 1,110 mg (total dose) of amphotericin B-deoxycholate for suspected or proven disseminated fungal infection. Amphotericin B concentrations were measured by high-pressure liquid chromato...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Collette, N, van der Auwera, P, Lopez, A P, Heymans, C, Meunier, F
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1989
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171494/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2658785/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.3.362
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