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Mode of action of 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine (BRL 39123) against herpes simplex virus in MRC-5 cells.

The metabolism and mode of action of 9-(4-hydroxy-3-hydroxymethylbut-1-yl)guanine (BRL 39123) were studied in herpes simplex virus type 1 (HSV-1)-infected and uninfected MRC-5 cells and compared with those of acyclovir. In uninfected cells incubated with 10 microM acyclonucleoside for 4 h, no phosph...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Hodge, R A, Perkins, R M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171461/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2541655/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.2.223
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