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Comparison of the efficacies of amphotericin B, fluconazole, and itraconazole against a systemic Candida albicans infection in normal and neutropenic mice.

We compared the efficacies of the new triazole antifungal drugs fluconazole and itraconazole with that of amphotericin B in vitro and in an animal model of systemic candidiasis in normal and neutropenic mice. Antifungal treatment with fluconazole (2.5 to 20 mg/kg orally twice daily), itraconazole (1...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Principais autores: Van t Wout, J W, Mattie, H, van Furth, R
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC171446/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2541654/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/aac.33.2.147
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