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Zidovudine antagonizes the action of pyrimethamine in experimental infection with Toxoplasma gondii.

The effect of zidovudine (azidothymidine; AZT) on the action of pyrimethamine against Toxoplasma gondii was investigated. Zidovudine was found to antagonize the toxoplasmacidal effect of low concentrations of pyrimethamine in vitro, and in vitro synergism of pyrimethamine and sulfadiazine against T....

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Detalhes bibliográficos
Main Authors: Israelski, D M, Tom, C, Remington, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1989
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC171416/
https://ncbi.nlm.nih.gov/pubmed/2712547
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