Φορτώνει......
Antithetic regulation by β-adrenergic receptors of G(q) receptor signaling via phospholipase C underlies the airway β-agonist paradox
β-adrenergic receptors (βARs) relax airway smooth muscle and bronchodilate, but chronic β-agonist treatment in asthma causes increased sensitivity to airway constriction (hyperreactivity) and is associated with exacerbations. This paradox was explored using mice with ablated βAR genes (βAR(–/–)) and...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
American Society for Clinical Investigation
2003
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC171392/ https://ncbi.nlm.nih.gov/pubmed/12925702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200318193 |
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