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A chemical approach for identifying O-GlcNAc-modified proteins in cells

The glycosylation of serine and threonine residues with a single GlcNAc moiety is a dynamic posttranslational modification of many nuclear and cytoplasmic proteins. We describe a chemical strategy directed toward identifying O-GlcNAc-modified proteins from living cells or proteins modified in vitro....

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Détails bibliographiques
Auteurs principaux: Vocadlo, David J., Hang, Howard C., Kim, Eun-Ju, Hanover, John A., Bertozzi, Carolyn R.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC171382/
https://ncbi.nlm.nih.gov/pubmed/12874386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1632821100
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