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Synthesis of deoxythymidylate and the unusual deoxynucleotide in mature DNA of Bacillus subtilis bacteriophage SP10 occurs by postreplicational modification of 5-hydroxymethyldeoxyuridylate.
Mature DNA of Bacillus subtilis W23 phage SP10 contains a hypermodified nucleotide (YdTMP) that replaces ca. 20% of the DTMP. SP10 DNA was pulse-labeled for 1 min at 20 degrees C with 32Pi. Among the oxopyrimidine nucleotides, virtually all of the radioactivity was recovered as 5-hydroxymethyldeoxyu...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
1981
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC171364/ https://ncbi.nlm.nih.gov/pubmed/6792371 |
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