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Suppression of antibodies to nucleic acids with polyinosinic-polycytidilic acid and cyclophosphamide in murine lupus
NZB/NZW mice with active lupus were treated with polyinosinic·polycytidylic acid, a synthetic double stranded RNA, followed by cyclophosphamide to induce immunologic tolerance to nucleic acids. This combined regimen reduced serum antibodies to RNA and DNA to a greater degree than did cyclophosphamid...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
1970
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1712882/ https://ncbi.nlm.nih.gov/pubmed/5493526 |
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