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Identification of point mutations in 41 unrelated patients affected with Menkes disease.

Genomic DNA of 41 unrelated patients affected with the classical severe form of Menkes disease was investigated for point mutations in the ATP7A gene (previously designated as the "MNK" gene). Using SSCP analysis and direct sequencing of the exons amplified by PCR, we identified 41 differe...

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Détails bibliographiques
Auteurs principaux: Tümer, Z, Lund, C, Tolshave, J, Vural, B, Tønnesen, T, Horn, N
Format: Artigo
Langue:Inglês
Publié: 1997
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1712537/
https://ncbi.nlm.nih.gov/pubmed/8981948
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