Study of a single BRCA2 mutation with high carrier frequency in a small population.

Germ-line changes in the cancer-predisposition gene BRCA2 are found in a small proportion of breast cancers. Mutations in the BRCA2 gene have been studied mainly in families with high risk of breast cancer in females, and male breast cancer also has been associated with BRCA2 mutations. The importan...

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Autori principali: Thorlacius, S, Sigurdsson, S, Bjarnadottir, H, Olafsdottir, G, Jonasson, J G, Tryggvadottir, L, Tulinius, H, Eyfjörd, J E
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1997
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1712443/
https://ncbi.nlm.nih.gov/pubmed/9150155
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