Haplotype and phylogenetic analyses suggest that one European-specific mtDNA background plays a role in the expression of Leber hereditary optic neuropathy by increasing the penetrance of the primary mutations 11778 and 14484.

Những quyển sách tương tự

• Detection of the mtDNA 14484 mutation on an African-specific haplotype: implications about its role in causing Leber hereditary optic neuropathy.
  Bằng: Torroni, A., et al.
  Được phát hành: (1996)
• Clustering of Caucasian Leber hereditary optic neuropathy patients containing the 11778 or 14484 mutations on an mtDNA lineage.
  Bằng: Brown, M D, et al.
  Được phát hành: (1997)
• About the "Asian"-specific 9-bp deletion of mtDNA....
  Bằng: Torroni, A, et al.
  Được phát hành: (1995)
• The 14484 ND6 mtDNA mutation in Leber hereditary optic neuropathy does not affect fibroblast complex I activity.
  Bằng: Cock, H R, et al.
  Được phát hành: (1995)
• mtDNA analysis reveals a major late Paleolithic population expansion from southwestern to northeastern Europe.
  Bằng: Torroni, A, et al.
  Được phát hành: (1998)