Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Cytochrome P450 2D6 (CYP2D6) metabolizes many important drugs. CYP2D6 activity ranges from complete deficiency to ultrafast metabolism, depending on at least 16 different known alleles. Their frequencies were determined in 589 unrelated German volunteers and correlated with enzyme activity measured...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Sachse, C, Brockmöller, J, Bauer, S, Roots, I
Format: Artigo
Jezik:Inglês
Izdano: 1997
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1712396/
https://ncbi.nlm.nih.gov/pubmed/9012401
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki