Cathepsin L in secretory vesicles functions as a prohormone-processing enzyme for production of the enkephalin peptide neurotransmitter

Multistep proteolytic mechanisms are essential for converting proprotein precursors into active peptide neurotransmitters and hormones. Cysteine proteases have been implicated in the processing of proenkephalin and other neuropeptide precursors. Although the papain family of cysteine proteases has b...

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Detalhes bibliográficos
Main Authors: Yasothornsrikul, Sukkid, Greenbaum, Doron, Medzihradszky, Katalin F., Toneff, Thomas, Bundey, Richard, Miller, Ruthellen, Schilling, Birgit, Petermann, Ivonne, Dehnert, Jessica, Logvinova, Anna, Goldsmith, Paul, Neveu, John M., Lane, William S., Gibson, Bradford, Reinheckel, Thomas, Peters, Christoph, Bogyo, Matthew, Hook, Vivian
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2003
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC170962/
https://ncbi.nlm.nih.gov/pubmed/12869695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1531542100
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