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Bad-deficient mice develop diffuse large B cell lymphoma

The proapoptotic activity of the “BH3-only” molecule BAD can be differentially regulated by survival factor signaling. Bad-deficient mice lacking both BAD long and BAD short proteins proved viable, and most cell types appeared to develop normally. BAD did not exclusively account for cell death after...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Ranger, Ann M., Zha, Jiping, Harada, Hisashi, Datta, Sandeep Robert, Danial, Nika N., Gilmore, Andrew P., Kutok, Jeffery L., Le Beau, Michelle M., Greenberg, Michael E., Korsmeyer, Stanley J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2003
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170917/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12876200/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1533446100
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