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The 1.1-Å resolution crystal structure of DJ-1, the protein mutated in autosomal recessive early onset Parkinson's disease

Mutations in DJ-1, a human gene with homologues in organisms from all kingdoms of life, have been shown to be associated with autosomal recessive, early onset Parkinson's disease (PARK7). We report here the three-dimensional structure of the DJ-1 protein, determined at a resolution of 1.1 Å by...

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Main Authors: Wilson, Mark A., Collins, Jennifer L., Hod, Yaacov, Ringe, Dagmar, Petsko, Gregory A.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2003
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC170905/
https://ncbi.nlm.nih.gov/pubmed/12855764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1133288100
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