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Differential binding of NAD(+) and NADH allows the transcriptional corepressor carboxyl-terminal binding protein to serve as a metabolic sensor

Carboxyl-terminal binding protein (CtBP) is a transcriptional corepressor originally identified through its ability to interact with adenovirus E1A. The finding that CtBP–E1A interactions were regulated by the nicotinamide adeninine dinucleotides NAD(+) and NADH raised the possibility that CtBP coul...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Fjeld, Clark C., Birdsong, William T., Goodman, Richard H.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2003
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC170896/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12872005/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.1633591100
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