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Why are mineralocorticoid receptor antagonists cardioprotective?

Two clinical trials, the Randomized ALdosterone Evaluation Study (RALES) and the EPlerenone HEart failure and SUrvival Study (EPHESUS), have recently shown that mineralocorticoid receptor (MR) antagonists reduce mortality in patients with heart failure on top of ACE inhibition. This effect could not...

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Autors principals: Chai, Wenxia, Danser, A. H. Jan
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1705472/
https://ncbi.nlm.nih.gov/pubmed/17075718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-006-0107-9
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