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The effect of caffeine on the mitosis of human lymphocytes in culture

1. The effect of caffeine at concentrations of 10(-2)M to 10(-4)M on the mitotic rate of phytohaemagglutinin-stimulated human lymphocytes from twelve normal subjects was examined in vitro. 2. At 10(-2)M the drug was cytotoxic. 3. At 10(-3)M caffeine reduced the rate of mitosis in all cases. 4. At 10...

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Detalhes bibliográficos
Autor principal: Timson, J.
Formato: Artigo
Idioma:Inglês
Publicado em: 1970
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702587/
https://ncbi.nlm.nih.gov/pubmed/5445691
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