The RNA-Binding Protein KSRP Promotes Decay of β-Catenin mRNA and Is Inactivated by PI3K-AKT Signaling

β-catenin plays an essential role in several biological events including cell fate determination, cell proliferation, and transformation. Here we report that β-catenin is encoded by a labile transcript whose half-life is prolonged by Wnt and phosphatidylinositol 3-kinase–AKT signaling. AKT phosphory...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Gherzi, Roberto, Trabucchi, Michele, Ponassi, Marco, Ruggiero, Tina, Corte, Giorgio, Moroni, Christoph, Chen, Ching-Yi, Khabar, Khalid S, Andersen, Jens S, Briata, Paola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2007
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1702562/
https://ncbi.nlm.nih.gov/pubmed/17177604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0050005
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller