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Activation of RegB endoribonuclease by S1 ribosomal protein requires an 11 nt conserved sequence
The T4 RegB endoribonuclease cleaves specifically in the middle of the -GGAG- sequence, leading to inactivation and degradation of early phage mRNAs. In vitro, RegB activity is very weak but can be enhanced 10- to 100-fold by the Escherichia coli ribosomal protein S1. Not all RNAs carrying the GGAG...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1702504/ https://ncbi.nlm.nih.gov/pubmed/17130171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl911 |
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