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Lack of sugar discrimination by human Pol µ requires a single glycine residue

DNA polymerase mu (Pol µ) is a novel family X DNA polymerase that has been suggested to play a role in micro-homology mediated joining and repair of double strand breaks. We show here that human Pol µ is not able to discriminate against the 2′-OH group of the sugar moiety. It inserts rNTPs with an e...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ruiz, José F., Juárez, Raquel, García-Díaz, Miguel, Terrados, Gloria, Picher, Angel J., González-Barrera, Sergio, Fernández de Henestrosa, Antonio R., Blanco, Luis
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2003
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC169901/
https://ncbi.nlm.nih.gov/pubmed/12888504
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